At the point when to test for HIV amid and after consummation of PEP?

September 6, 2017 | By admin123 | Filed in: Blog.

I get this inquiry a ton.

Above all else, information on this is missing and difficult to find.

There are numerous speculations that theorize that PEP decreases viral replication and deferrals sero-transformation and accordingly make HIV testing less precise. These hypotheses have nor been demonstrated nor exposed.

Moreover, there is exceptionally restricted information on the utilization of P24 antigen tests (counting Combo/Duo tests) and viral load testing for symptomatic purposes in quiet who have or experiencing PEP. Actually, considers on monkeys (and more restricted examinations on people) have demonstrated constructive viral load tests in people who were in this way observed not to be tainted. This could speak to a prematurely ended disease (which is the thing that PEP Post Exposure Prophylaxis should and intended to do) instead of a genuine false positive. This delineates one of the impediments of utilizing viral load tests to analyze individuals as of now on or have finished PEP.

Official Guidelines

The US CDC Guidelines on Antiretroviral Postexposure Prophylaxis After Sexual, Injection-Drug Use, or Other Nonoccupational Exposure to HIV in the United States prescribes that patients ought to be tried for the nearness of HIV antibodies at benchmark, 4 – a month and a half, 3 months and a half year post presentation.

The Joint WHO/ILO rules on post-introduction prophylaxis (PEP) to forestall HIV contamination prescribes HIV testing at benchmark, promptly subsequent to finishing PEP (i.e. 4 to a month and a half post introduction) and once more ‘3 – a half year post presentation’.

The 2 rules are somewhat comparative despite the fact that the US CDC is by all accounts all the more firm on the necessity of a test at a half year contrasted with the WHO rules.

Recently, the New York State Department of Health AIDS Institute’s grown-up HIV rules advisory group embraced an extensive re-assessment of its HIV word related PEP rules and issued a few changes which included shortening of the season of HIV testing after introduction to 3 months if present day, blood based, standard HIV testing is performed. This is unquestionably encouraging anyway it alludes to word related HIV presentation just and similar information and proposal may not be stretched out to non-word related introduction.

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